E45 dermatological cream treatment for dry skin. E45 Cream is clinically proven to be effective and comfortable for treating and soothing dry, itchy, flaky, cracked, rough and calloused skin, sunburn and cleaning products. The non-greasy and emollient formulation is quickly absorbed by the skin, making it soft, pleasant and relieving. The E45 cream is recommended for more severe dry skin conditions such as eczema, dermatitis, ichthyosis and certain dry cases of psoriasis. E45 cream can be used daily by the whole family including babies.